Figure 4

Trypanosoma dionisii as an experimental model to study anti-Trypanosoma cruzi drugs: A comparative analysis with benznidazole, posaconazole and amiodarone

De Souza W*, Barrias ES and Borges TR

Published: 17 October, 2018 | Volume 1 - Issue 1 | Pages: 014-023

ijcmbt-aid1003-g004

Figure 4:

Transmission electron micrographs of T. dionisii epimastigotes treated with posaconazole and amiodarone (B–D). (A) Control cell with normal morphology (N, nucleus; k, kinetoplast; F, flagellum). (B) Epimastigotes treated with 1 nM posaconazole showed an intense disorganization of Golgi complex (asterisks). (C–D) Amiodarone treatment (0.5 µM) causes mitochondrial swelling (m) and membrane blebs (b) at the parasite flagellum after 48 hours.

Read Full Article HTML DOI: 10.29328/journal.ijcmbt.1001003 Cite this Article Read Full Article PDF

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