Figure 2

Trypanosoma dionisii as an experimental model to study anti-Trypanosoma cruzi drugs: A comparative analysis with benznidazole, posaconazole and amiodarone

De Souza W*, Barrias ES and Borges TR

Published: 17 October, 2018 | Volume 1 - Issue 1 | Pages: 014-023


Figure 2:

Treatment of peritoneal macrophages infected with amastigotes of T. cruzii or T. dionisii with benznidazole. (A), posaconazole (B) and amiodarone (C) inhibits amastigotes’ multiplication at different concentrations depending on the Trypanosoma species used. The drug was added in the macrophage cultures after 24 h of interaction, when most of the cells were infected. Every day, the association indices were determined (mean number of parasites internalized multiplied by the percentage of infected macrophages divided by the total number of macrophages). The results are expressed as the mean of three independent experiments.

Read Full Article HTML DOI: 10.29328/journal.ijcmbt.1001003 Cite this Article Read Full Article PDF

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